Smart aiegens promise effective theranostics
WebSep 8, 2016 · Smart design of simple molecules born with multifunctions should represent one of the future directions in theranostics. Fluorogens with aggregation-induced … WebTheranostics 2024 TLDR It is believed that AIEgens would be promising multifunctional theranostic platforms in clinical fields and facilitate significant advancements in this …
Smart aiegens promise effective theranostics
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WebOct 6, 2024 · In this minireview, we summarize the recent advances of photodynamic NIR-II aggregation-induced emission luminogens (AIEgens) for biomedical applications. The molecular design strategies for tuning the electronic bandgaps and photophysical energy transformation processes are discussed. WebThis review highlights the tremendous aggregation‐enhanced superiorities of AIE luminogens (AIEgens) in disease theranostics mainly involving diagnostic imaging (fluorescence and room temperature phosphorescence), therapeutic intervention (photodynamic therapy), and feasibility in construction of multi‐modality theranostic …
WebApr 4, 2024 · As an antibiotic-free therapy, phototherapy is a promising approach to treat microbial infections due to its spatiotemporal selectivity, non-invasiveness, minimal side … WebAggregation-induced emission luminogens (AIEgens) that display strong emission in aggregated states, low background, high signal-to-noise ratio and sensitivity, and high resistance to photobleaching, may circumvent this problem. On the other hand, the overuse of anti-bacterial antibiotics diminishes their effect.
WebDec 3, 2024 · The induction of mitochondrial dysfunction can be an effective pathway of chemotherapy, photodynamic therapy, and combination therapy against cancer. This review focuses on recent progress in the field of AIE luminogens (AIEgens) for cancer theranostics based on mitochondrial targeting and dysfunction. WebOrganometallic AIEgens (OMAs) possess the merits of both AIEgens (affording “turn-on” type probes in vitro and in vivo) and metal ions (enhancing electron transfer and …
WebNov 19, 2024 · In this work, an enzyme‐mediated aggregation‐induced emission fluorogen (AIEgen) intracellular polymerization strategy that can simultaneously promote the accumulation and retention of the AIEgen in the tumor for prolonged imaging and enhanced tumor growth inhibition is described. An AIEgen‐peptide conjugate (D2P1) and… View on …
WebMay 1, 2024 · Excellent activatable AIE probes have been reported for detecting toxic substances, imaging intracellular active molecules/biomolecules, as well as monitoring … the prince mawdlamWebSep 9, 2024 · Many AIEgens have been successfully designed, synthesized, and further applied for molecular imaging and image-guided theranostics in neurological diseases … the prince mangaWebSmart design of simple molecules born with multifunctions should represent one of the future directions in theranostics. Fluorogens with aggregation-induced emission … sigil of arathor wowWebThis research has therefore presented a smart multifunctional material holding great promise in both basic research and clinical practice. Cancer as a leading cause of death in recent decades has been paying close attention owing to … the prince metallicaWebAs shown here, AIEgen-based theranostic systems have been extensively investigated and demonstrated to be promising candidates in improving the treatment efficacy. Highly … sigil of awarenessWebTo facilitate image-guided theranostics, researchers usually apply a desired amount of photosensitizers to achieve effective photothermal responses. However, these probes could easily suffer from low photostability and aggregated-caused quenching effect … the prince melbourneWebAggregation-induced emission (AIE) is an inventive fluorescent technique and has the potential to address this issue. 4,33–51 AIE illustrates a unique photophysical phenomenon where molecules are non-emissive in the discrete state because of active intramolecular motions, but emit energetically when aggregated due to the restriction of … the prince maurice mauritius