Rnf13
WebDec 21, 2024 · RNF13 is a critical mediator for facilitating endoplasmic reticulum stress-induced apoptosis through the activation of the IRE1alpha-TRAF2-JNK signaling pathway. … WebFIGURE 2 RNF13 is highly enriched in the microsomal ER fraction, and both the ER localization and functional RING domain are required for RNF13-induced apoptosis. A, …
Rnf13
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WebFeb 22, 2014 · Satellite cells proliferate more rapidly in RNF13-/-mice than in RNF13 +/+ mice. The improved skeletal muscle regeneration following injury in RNF13-/-mice … WebProtein Mutation Frequency in Cancer. The 'lollipop plot' above illustrates recurrent (observed in 3 or more out of 4440 TCGA tumor samples from 15 cancer types) and …
RING finger protein 13 is a protein that in humans is encoded by the RNF13 gene. The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. The specific function of this gene has not yet been determined. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported. WebRNF13, a RING finger protein, mediates endoplasmic reticulum stress-induced apoptosis through the inositol-requiring enzyme (IRE1α)/c-jun NH 2-terminal kinase pathway. Journal of Biological Chemistry 288 (12) : 8726-8736.
WebFIGURE 2 RNF13 is highly enriched in the microsomal ER fraction, and both the ER localization and functional RING domain are required for RNF13-induced apoptosis. A, mitochondrial, microsomal ER, and cytosolic fractions of 293T cells transfected with Myc-RNF13 were prepared as described under “Materials and Methods.” WebAnti RNF13 pAb [Catalog No.: ATL-HPA064784] Neurodegeneration Products. CUSABIO dashboard. Fukushima Cancer Gene Overexpressing Cell Lines. ubiquitin proteasome …
Web609247 - RING FINGER PROTEIN 13; RNF13 - RNF13 In 3 unrelated patients with developmental and epileptic encephalopathy-73 (DEE73; 618379), Edvardson et al. (2024) …
WebNov 6, 2024 · Developmental and epileptic encephalopathies (DEE) are rare and serious neurological disorders characterized by severe epilepsy with refractory seizures and a … k12d エンジンWebOct 6, 2024 · Objective . To study the biological function of circular RNA RNF13 (circRNF13) in acute myeloid leukemia (AML) and its relationship with prognosis. Methods . We constructed stable AML cell lines with downregulated expression of circRNF13, and then, we explored the effect of downregulation of circRNF13 expression on the proliferation, … adverse obsolescence definitionWebJul 4, 2024 · The objective of this study was to understand if RNF13 can affect Parkinson's disease (PD) model mice by modulating the endoplasmic reticulum stress (ERS)-mediated IRE1α-TRAF2-ASK1-JNK pathway. C57BL/6 mice injected with MPTP to establish PD mice models were divided into Control, MPTP, MPTP + sh-RNF13, and MPTP + sh-NC groups. k10 レイヤー ダイヤモンド ネックレスWebOct 21, 2010 · The RNF13 gene is located at chromosome 3q25.1 in human and is evolutionarily conserved in many metazoans including the chimpanzee, dog, cow, chicken, … k12d スズキWebFeb 22, 2014 · RING finger protein 13 (RNF13) is a newly identified E3 ligase reported to be functionally significant in the regulation of cancer development, muscle cell growth, and … k11 韓国の反応WebARF4, ARF2, ADP ribosylation factor 4. معرفات خارجية. الوراثة المندلية البشرية عبر الإنترنت 601177 MGI: MGI:99433 HomoloGene: 55593 GeneCards: 378. علم الوجود الجيني. الوظيفة الجزيئية. • nucleotide binding. • epidermal growth factor receptor binding. • GTP binding. k10 読み方WebRING finger protein 13 (RNF13) is a newly identified E3 ligase reported to be functionally significant in the regulation of cancer development, muscle cell growth, and neuronal development. In this study, the function of RNF13 in cardiotoxin-induced skeletal muscle regeneration was investigated using RNF13 -knockout mice. RNF13 >-/- mice … k12c エンジン